Digital chemistry and catalysis: redefining reactions in confined systems

'From sunscreens to vaccines, most of the modern technology we rely on today is dependent on our ability to precisely manufacture complex molecules with precise chemical properties. However, conventional batch synthesis approaches have a number of common limitations - process complexity and cost, excessive consumption of resources such as time and reagents, poor reproducibility, and more.  Safety issues can also play a major role when the reaction in concern is exothermic and potentially explosive due to the large volumes involved in batch manufacturing. To address these challenges, we have developed a unique, ground-breaking technology for molecular manufacturing via digital catalysis that will not only enable precise on-demand synthesis of existing, widely used chemicals but will also enable the exploration of entirely new chemical systems. Built on our extensive experience in nanotechnology, biochemistry, electrochemistry, and microfluidics, this technology will redefine the landscape of chemical synthesis and manufacturing.

Our interdisciplinary team, led by ARC Laureate Fellow Professor Matt Trau, is seeking passionate and motivated PhD scholars to join us in unlocking the transformative potential of this technology. Interested students will have the opportunity to learn a variety of skills across a broad set of fields - including nano-fabrication, computer simulation, physical chemistry, and molecular biology.

This multidisciplinary PhD project will be undertaken within the Australian Institute for Bioengineering and Nanotechnology (AIBN) in Professor Trau's Group at UQ and its affiliated institutes and centres, specifically the Australian National Fabrication Facility (ANFF, Queensland Node), Centre for Microscopy, Microanalysis (CMM) and the Centre for Advance Imaging (CAI).  AIBN has created a world-class environment for nanotechnology and bioengineering researchers (>400 alone at AIBN), making the AIBN and Uq the ideal place to conduct the proposed research in an efficient manner to ensure success.  Because of the breadth of application of this program, the research involves interdisciplinary components that involve physical chemistry, nanoscience, colloid and interface science, biomolecular chemistry, epigenetics and fluid dynamic modeling and the utilisation of artificial intelligence algorithms.

This is an Fellowship support scheme scholarship project that aligns with a recently awarded Australian Government grant.

The scholarship includes:

• living stipend of $36,400 per annum tax free (2025 rate), indexed annually
• your tuition fees covered
• single overseas student health cover (OSHC).

Learn more about the Fellowship support scheme scholarship.

Your application will be assessed on a competitive basis.

We take into account your:

• previous academic record
• publication record
• honours and awards
• employment history.

A working knowledge of different microfabrication processes and CFD simulation software(s) would be of benefit to someone working on this project.

You will demonstrate academic achievement in the field(s) of medical / life sciences, chemistry, biochemistry, biomedical Engineering and relevant disciplines, and the potential for scholastic success.

A background or knowledge of fluid flow dynamics is highly desirable.

This project requires candidates to commence no later than Research Quarter 4, 2026. You can start in an earlier research quarter.

You must submit an expression of interest (EOI) by the closing date for the research quarter (RQ) you want to start in:

Before you apply

1. Check your eligibility for the Doctor of Philosophy (PhD).
2. Prepare your documentation.
3. If you have any questions about whether the project is suitable for your research interests, contact Professor Matt Trau (trau.enquiries@uq.edu.au).

When you apply

To apply, submit an expression of interest (EOI) for the program. You don't need to apply separately for the project or scholarship. How to submit an EOI

In your EOI, complete the 'Scholarship/Sponsorship' section with the following details:

1. Are you applying for an advertised project: 'Yes'
2. Project: 'Fellowship project scholarship'
3. Scholarship Code Listed in the Advertisement: TRAU-291123
4. Link to Scholarship Advertisement: https://study.uq.edu.au/study-options/phd-mphil-professional-doctorate/projects/digital-chemistry-and-catalysis-redefining-reactions-confined-systems

Submit an EOI